How Long to Bake Lasagna at 375°F – (in Oven)

Today, we will cook perfect lasagna, specifically focusing on the baking magic that happens at 375°F with oven-ready noodles. If you’ve ever wondered how long to bake lasagna with those convenient oven-ready noodles, you’re in for a treat.

Join me as we explore the simple yet crucial steps to achieving your oven-baked lasagna’s ideal texture and flavor.


  • This lasagna recipe is ideal for holiday gatherings, making it a crowd-pleaser with its delicious layers of flavors.
  • The recipe simplifies the lasagna-making process, ensuring a stress-free cooking experience even for beginners.
  • The carefully crafted meat sauce perfectly balances with added seasonings, creating a rich and savory taste.
  • The Cajun seasoning in the ricotta cheese mixture adds a unique twist, elevating the dish with unexpected and delightful flavors.
  • Baking at 375°F for 45-50 minutes guarantees a mouthwatering lasagna with perfectly melted cheese and well-cooked noodles.

How Long to Bake Lasagna at 375°F

Bake lasagna at 375°F for 45-50 minutes, covering it with foil for the first hour and broiling it uncovered for the final 3 minutes for a golden, cheesy finish.

How to Bake Lasagna at 375

To bake lasagna at 375°F, assemble layers of cooked meat sauce, lasagna noodles, and cheese in a casserole dish. Cover with foil, bake for 45-50 minutes, remove foil, broil for 3 minutes, then let it rest for 5 minutes before serving.

Bake Lasagna at 375 Recipe

Bake Lasagna at 375 Recipe

Yield: 8 servings
Prep Time: 40 minutes
Cook Time: 50 minutes
Total Time: 1 hour 30 minutes

Enjoy your delicious lasagna!


  • 2.5 pounds of 80/20 ground beef
  • Chopped onions
  • Garlic
  • Tomato sauce
  • Fresh parsley
  • Lasagna noodles
  • Grated Parmesan cheese
  • Fresh mozzarella cheese
  • Ricotta cheese mixture (Parmesan, garlic powder, parsley, one egg, Cajun seasoning, black pepper, and a pinch of salt)


  • Skillet
  • Casserole Dish
  • Mixing Bowl
  • Spoon
  • Spatula
  • Foil
  • Non-stick cooking spray


Let's begin with the step-by-step Lasagna recipe baking at 375°F guide!

Step 1: Preparing the Meat Sauce

  • Cook ground beef on high heat until it begins to caramelize.
  • Drain excess fat and create a well in the center.
  • Add chopped onions, seasonings, and garlic, stir until fragrant.
  • Pour in tomato sauce and simmer on medium-low heat for 30 minutes.
  • Taste the sauce and adjust with sugar to balance acidity.
  • Add fresh parsley and let it simmer.

Step 2: Ricotta Cheese Mixture

Ricotta Cheese Mixture

  • In a bowl, mix grated Parmesan cheese, garlic powder, parsley, one egg, Cajun seasoning, black pepper, and a pinch of salt.
  • Adjust seasoning to taste.

Step 3: Assembling the Lasagna

Assembling the Lasagna

  • Preheat the oven to 375°F.
  • In a casserole dish, spread a layer of meat sauce to prevent noodles from sticking.
  • Place a layer of lasagna noodles, slightly overlapping.
  • Add another layer of meat sauce, Parmesan cheese, and fresh mozzarella.
  • Repeat the process with additional layers until ingredients are used up.
  • Finish with a final layer of meat sauce and top with a generous amount of fresh mozzarella.

Step 4: Baking


  • Cover the dish with foil, ensuring it's lightly sprayed with non-stick cooking spray.
  • Bake in the preheated oven at 375°F for 45-50 minutes.
  • After an hour, remove the foil.
  • Set the oven to broil at 500°F and broil for an additional 3 minutes, keeping a close eye to avoid burning.

Step 5: Resting and Serving

Bake Lasagna at 375

  • Let the lasagna rest for about 5 minutes before serving to prevent it from falling apart.
  • Cut into squares, serve, and enjoy!

FAQ – Frequently Asked Questions

Can I substitute ground beef with another meat or go vegetarian?

You can use ground turkey, chicken, or even a meat substitute for a lighter option. Consider using a mix of sautéed vegetables or plant-based meat alternatives for a vegetarian version.

How can I avoid the lasagna noodles from sticking together?

Adding a thin layer of meat sauce at the bottom of the casserole dish before placing the noodles helps prevent sticking. Ensure the noodles are slightly overlapping, and press them down gently.

Can I use no-boil lasagna noodles for this recipe?

Yes, you can use no-boil lasagna noodles. Adjust the baking time accordingly, as no-boil noodles may require less time in the oven.

Is it necessary to use fresh mozzarella, or can I use shredded mozzarella from the store?

Either will work! Fresh mozzarella can provide a creamier texture, but shredded mozzarella is a convenient alternative. Use your preference or a combination of both.

My lasagna turned out a bit watery. How can I avoid this?

Ensure the meat sauce is well-simmered to evaporate excess moisture. Additionally, make sure the ricotta mixture is not too wet, and consider letting the lasagna rest longer after baking to allow excess moisture to settle.

Can I customize the seasonings in the ricotta mixture?

 The ricotta mixture is flexible. Adjust the seasonings to your taste, and feel free to add herbs or spices that you enjoy.

What side dishes pair well with lasagna?

Classic choices include a fresh green salad, garlic bread, or roasted vegetables. Choose sides that complement the richness of the lasagna.


This lasagna is not only delicious but also easy to make. I can’t wait for you to try it out! If you do, come back and share your experience in the comments. Happy cooking, and have a fantastic holiday season!

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